Evaluation of Exposure Assessment Tools under REACH: Part II—Higher Tier Tools

Between-User Reliability of Tier 1 Exposure Assessment Tools Used Under REACH.

When applying simple screening (Tier 1) tools to estimate exposure to chemicals in a given exposure situation under the Registration, Evaluation, Authorisation and restriction of CHemicals Regulation 2006 (REACH), users must select from several possible input parameters. Previous studies have suggested that results from exposure assessments using expert judgement and from the use of modelling t...

Evaluation and Ranking of Discrete Simulation Tools

In studying through simulation, choosing an appropriate tool/language would be a difficult task because many of them are available. On the other hand, few research works focus on evaluation of simulation tools/languages and their comparison. This paper makes a couple of evaluations and ranks more than fifty simulation tools that are currently available. The first evaluation and ranking is in th...

Exposure-based waiving under REACH.

Within the REACH framework, but also within OECD, there is understanding that for reasons of animal welfare, costs and logistics, it is important to limit the number of tests to be conducted. Exposure-based waiving (EBW) is a potentially important element in testing strategies. This publication describes criteria for exposure-based waiving as foreseen in the REACH regulation and gives more deta...

Frailty Screening Tools: Frail Detection to Primary Assessment

Frailty is a vulnerable situation among older adults which can lead to unfavorable health outcomes such as falls, mortality, functional decline and institutionalization. The increasing number of elderly people and low rate of mortality has necessitated the need for high-quality medical services for this aging population, and this has led to a high cost of geriatric health care. There exist a hu...

Approaches and Tools for Higher Tier Assessment of Environmental Fate in the Uk